维生素D对青少年初级失经症的影响
Ainur Donayeva1, Ainur Amanzholkyzy1, Ibrahim Abdelazim2
1Department of Normal Physiology, West Kazakhstan Marat Ospanov Medical University, Aktobe, Kazakhstan.
Journal of medicine and life
|February 26, 2024
概括
维生素D补充剂显著减少了青少年患有原发性经期障碍的疼痛. 这项研究表明,维生素D是治疗月经疼痛和减少对NSAIDs依赖的潜在治疗选择.
科学领域:
- 生殖内分泌学 生殖内分泌学
- 营养科学 营养科学
- 疼痛管理 疼痛管理
背景情况:
- 维生素D受体 (VDR) 存在于女性生殖系统中,影响炎症性细胞因子和前列腺素合成.
- 主要经期不良,以痛苦的月经为特征,显著影响青少年的生活质量.
研究的目的:
- 为了研究维生素D对青少年初级失经症的治疗作用.
- 探索维生素D水平与原发性厌经症的严重程度之间的关系.
主要方法:
- 八十五名患有初级更年障碍的青少年被录取.
- 盆腔超声波排除了盆腔病理;血液测试测量了TSH,益生菌素,HbA1C和25-氧维生素D (25[OH]D).
- 参与者接受维生素D (5万IU每周五个月),疼痛通过视觉模拟量表 (VAS) 和口头多维评分 (VMS) 治疗前后评估.
主要成果:
- 半月的VAS和VMS平均得分从8.7±0.91和2.65±0.93显著下降到4.8±0.75和0.80±0.75 (p=0.03和0.025).
- 在25-基维生素D水平和VAS (R = -0.886;p<0.00001) 和VMS (R = -0.885;p<0.00001) 评分之间发现了强烈的负相关性.
结论:
- 维生素D补充剂是一种有效的治疗策略,可以减少青少年初级经期障碍症的严重程度.
- 维生素D可以作为治疗月经疼痛的非类固醇抗炎药物 (NSAIDs) 的可行的替代品.
关键词:
25 (((OH) D:25-基维生素 D 的含量为25-基维生素 D.美国糖尿病协会:美国糖尿病协会.美国生殖医学协会:美国生殖医学协会.体重指数 (BMI):身体质量指数.欧洲人类生殖和胚胎学会 (ESHRE):欧洲人类生殖和胚胎学会.HbA1C:糖基化血红蛋白:一种血红蛋白.无固醇抗炎药物:非类固醇抗炎药物.多囊性卵巢综合症:多囊性卵巢综合症.孕产妇前列腺素:前列腺素的前列腺素质量生活:生活质量.甲状腺刺激激素 (TSH):甲状腺刺激激素.VAS:视觉模拟尺度的视觉模拟尺度VDR:维生素D受体 维生素D受体VMS:口头多维分数系统.这是维生素. D:维生素D:维生素D是一种维生素.西哈萨克斯坦大学:西哈萨克斯坦大学.青少年 青少年 青少年经期不良的 经期不良 经期不良维生素D是维生素D的重要组成部分.更多相关视频
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