系统血压和心力衰竭患者高血压死亡率之间的相关性
Xueyan Lang1,2, Cheng Peng1,2, Yanxiu Zhang1,2
1The Department of Cardiology, the Second Affiliated Hospital of Harbin Medical University.
Journal of hypertension
|February 26, 2024
概括
静脉血压低于130mmHg与心力衰竭中较高的死亡率有关,心力衰竭患者的降低喷射率 (HFrEF) 患者. 这一趋势也在心力衰竭中与中等射出分数 (HFmrEF) 观察到,但不是在HFpEF中.
科学领域:
- 心脏病学 心脏病学
- 高血压研究 高血压研究
- 心脏衰竭研究研究
背景情况:
- 对高血压心力衰竭 (HF) 患者的最佳缩血压 (SBP) 目标,其射出分数 (EF) 不同,尚未得到充分确立.
- 以前的研究还没有充分探讨不同HF表型中SBP和死亡率之间的关系.
研究的目的:
- 研究所有心力衰竭 (HF) 现型中高血压患者的SBP水平和预后之间的关联.
- 为了确定SBP<130 mmHg是否对心力衰竭的死亡率产生不同的影响,减少喷射率 (HFrEF),中等射程喷射率 (HFmrEF) 和保存喷射率 (HFpEF).
主要方法:
- 一项回顾性队列研究分析了1279名高血压HF患者.
- 患者被分为SBP<130 mmHg (383名患者) 和SBP≥130 mmHg (896名患者) 的两组.
- 主要终点是1年随访期间的全因死亡率.
主要成果:
- 在HFrEF患者中,SBP<130 mmHg与所有原因死亡率 (HR 2.53) 和心血管死亡率 (HR 1.91) 的增加显著相关.
- 在SBP<130 mmHg的HFmrEF患者中观察到死亡率增加的趋势,尽管在统计学上不显著.
- 在SBP<130 mmHg的HFpEF患者中没有观察到增加的死亡风险.
结论:
- 低缩血压 (<130 mmHg) 与高高压患者的全因和心血管死亡率较高有关.
- 较低的SBP和死亡风险之间的关联在HFmrEF患者中显示出趋势,但在HFpEF患者中并不明显.
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