在任务空间中剖析肌肉协同作用
David O'Reilly1, Ioannis Delis1
1School of Biomedical Sciences, University of Leeds, Leeds, United Kingdom.
eLife
|February 26, 2024
概括
这项研究引入了一种理解肌肉协同作用的新方法,揭示了肌肉相互作用如何与任务无关,冗余或协同作用. 这一框架为各种任务的运动控制和协调提供了更深入的见解.
科学领域:
- 神经科学是一个神经科学.
- 发动机控制器的控制器
- 生物物理学的生物物理.
背景情况:
- 肌肉协同是运动控制的一个关键概念,解释了肌肉如何协调任务执行.
- 目前对肌肉相互作用的理解缺乏关于特定任务角色的详细表征.
- 现有的模型不能完全捕捉肌肉协同工作的细微方式.
研究的目的:
- 通过根据任务相关性为肌肉合分配特定的功能角色,提出关于肌肉协同作用的新视角.
- 将肌肉相互作用分为与任务无关的,冗余的和协同的类别.
- 为了提供一个更细微的了解如何肌肉相互作用有助于任务目标.
主要方法:
- 杆信息和网络理论,以及缩小维度的方法.
- 将离散和连续任务参数直接集成到肌肉协同提取中.
- 引入了共同信息作为衡量肌肉相互作用任务相关性的措施.
主要成果:
- 开发了一个框架,将肌肉相互作用归类为与任务无关,冗余或协同作用.
- 证明了框架在现实世界数据集上的功能和生理相关性.
- 提取了肌肉合和时间模式的可概括表示,反映了任务-目标相互作用.
结论:
- 拟议的框架为肌肉协同提供了一个细微的视角,超越了肌肉"一起工作"的简单概念.
- 确定了肌肉相互作用的不同功能角色,增强了我们对运动协调的理解.
- 通过统一当前的方法并提供新的见解,为运动控制研究开辟了新的途径.
关键词:
计算生物学是计算生物学.人类 人类 人类 人类 人类 人类 人类互动信息 互动信息运动协调运动协调肌肉网络 肌肉网络 肌肉网络肌肉协同作用 肌肉协同作用网络信息框架 网络信息框架神经科学 神经科学更多关于 裁员 裁员系统生物学 系统生物学更多相关视频
16:23Fiber Connections of the Supplementary Motor Area Revisited: Methodology of Fiber Dissection, DTI, and Three Dimensional Documentation
Published on: May 23, 2017
11.3K
06:12Dissection of the Transversus Abdominis Muscle for Whole-mount Neuromuscular Junction Analysis
Published on: January 11, 2014
11.7K
相关概念视频
Muscle Coordination and Action
1.5K
Muscle coordination is a complex and finely tuned process essential for smooth and purposeful movements like flexion, extension, adduction, abduction, and rotation. The human body orchestrates the actions of various muscles working in concert, each with a specific role. Four functional types describe how muscles work together: agonist, antagonist, synergist, and fixator.
Agonists
Agonist muscles, often called prime movers, are the primary muscles responsible for producing a specific movement....
Agonists
Agonist muscles, often called prime movers, are the primary muscles responsible for producing a specific movement....
1.5K
Fascicle Arrangement in Skeletal Muscles
2.0K
Fascicles are bundles of muscle fibers in a skeletal muscle. Muscle fascicle arrangement is directly associated with the power and range of motion of various muscles. The configuration of these fascicles can vary, leading to different functional outcomes.
The four primary types of muscle based on fascicle arrangement are:
The four primary types of muscle based on fascicle arrangement are:
2.0K
Structure and Organization of Smooth Muscles
5.7K
Smooth muscle tissue is a type of muscle tissue that can be found lining various vital organs in the human body, including the lungs, blood vessels, digestive tract, and respiratory tract. This type of tissue is responsible for regulating the movements of these organs, playing crucial roles in the functioning of various systems, including the vascular, digestive, respiratory, and urinary systems.
Structure of smooth muscle cell
Smooth muscle cells are spindle-shaped with tapering ends and a...
Structure of smooth muscle cell
Smooth muscle cells are spindle-shaped with tapering ends and a...
5.7K
Excitation-Contraction Coupling in Skeletal Muscles
8.2K
Excitation-contraction coupling is a series of events that occur between generating an action potential and initiating a muscle contraction. It occurs at the triad, a structure found in skeletal muscle fibers that comprise a T-tubule and terminal cisternae of the sarcoplasmic reticulum on each side. These triads are visible in longitudinally sectioned muscle fibers. They are typically located at the A-I junction — the junction between the A and I bands of the sarcomere.
When an action...
When an action...
8.2K
Space Trusses: Problem Solving
586
A space truss is a three-dimensional counterpart of a planar truss. These structures consist of members connected at their ends, often utilizing ball-and-socket joints to create a stable and versatile framework. Due to its adaptability and capacity to withstand complex loads, the space truss is widely used in various construction projects.
Consider a tripod consisting of a tetrahedral space truss with a ball-and-socket joint at C. Suppose the height and lengths of the horizontal and vertical...
Consider a tripod consisting of a tetrahedral space truss with a ball-and-socket joint at C. Suppose the height and lengths of the horizontal and vertical...
586
Motor Units
4.0K
The motor unit is a fundamental component of the neuromuscular system and plays a crucial role in coordinating muscle contractions. It consists of a somatic motor neuron, which connects and controls multiple skeletal muscle fibers, forming a single functional segment. The axon of the motor neuron branches out and establishes synaptic connections known as neuromuscular junctions with individual muscle fibers within the motor unit.
Motor units come in different sizes, with smaller units...
Motor units come in different sizes, with smaller units...
4.0K
