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Measuring Axonal Cargo Transport in Mouse Primary Cortical Cultured Neurons
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迪内因和迪纳克丁可以远程移动,但分别被送到轴突尖端

Alexander D Fellows1, Michaela Bruntraeger2, Thomas Burgold2

  • 1Division of Structural Studies, Medical Research Council Laboratory of Molecular Biology, Cambridge, UK.

The Journal of cell biology
|February 26, 2024
PubMed
概括

神经元使用dynein电机进行关键的轴突运输. 这项研究可视化了dynein及其调节器LIS1和NDEL1,揭示了它们如何沿着轴突协调长途运输.

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