动力学,扩展性脊髓学,以及唾液替代品的性
Karim Al Zahabi1, Lena Hassan1, Ramiro Maldonado1
1Department of Chemical Engineering, University of Illinois at Chicago, Chicago, IL 60607, USA. viveks@uic.edu.
Soft matter
|February 26, 2024
概括
大多数唾液替代品都无法模仿天然唾液的流动特性,特别是它的"紧性". 新的风湿学测试揭示了显著的差异,突出了开发有效配方的挑战,如食障碍等条件.
科学领域:
- 生物材料科学 生物材料科学
- 类风病学 类风病学 类风病学
- 口腔生物学 口腔生物学
背景情况:
- 唾液替代品对于医学,食品和制药研究至关重要,旨在复制人类唾液的复杂性质.
- 目前的风湿学评估往往忽视延伸性质,主要关注剪切粘度,该粘度无法捕获唾液的唾液.
- 连接性 性 性
- 也可以说是spinnbarkeit.
研究的目的:
- 综合评估十二种商业唾液替代品的风湿性质,包括扩展性行为.
- 为了比较这些替代品与天然唾液的性能.
- 探索滴滴对基板 (DoS) 类风湿学在设计仿生流体和诊断方面的潜力.
主要方法:
- 使用扭转类风湿法来测量取决于速率的剪切粘度.
- 采用滴滴对基板 (DoS) 协议来表征延伸性风湿学.
- 将替代品的风湿学数据与自然人唾液的数据进行比较.
主要成果:
- 在12种唾液替代品中,只有3种表现出可测量的粘性弹性和应变硬化.
- 没有一个测试的替代品成功地复制了天然唾液特征的剪切速率的粘度降低.
- 测试的替代品与感知到的替代品不匹配.
- 连接性 性 性
- 或是天然唾液的旋转性.
结论:
- 商业唾液替代品在很大程度上无法模仿天然唾液的复杂的质特征,特别是其延伸性质.
- 现有的配方可能无法充分满足需要唾液替代的患者的需求,例如患有失 ?? 症的患者.
- DoS类风湿测量为先进生物仿真流体配方的开发和诊断评估提供了一个有前途的工具.
相关概念视频
01:23Salivary Glands and Saliva
681
The salivary glands, of which there are three pairs known as the parotid, submandibular, and sublingual glands, play a crucial role in maintaining oral health and initiating the digestive process. Positioned near the ears, beneath the masseter muscle, the parotid glands secrete saliva into the oral cavity through the parotid duct of Stensen. Meanwhile, the submandibular glands, located on the floor of the mouth, secrete saliva through channels named submandibular ducts. The sublingual glands,...
681
01:27Types of Fluids
254
Fluids can be classified into Newtonian and non-Newtonian fluids based on their response to shear stress. Newtonian fluids have a linear relationship between shear stress and the shear strain rate, following Newton's law of viscosity. Their viscosity remains constant regardless of the shear rate, making their behavior predictable and easier to analyze. Common examples include water, air, oil, and gasoline.
In contrast, non-Newtonian fluids do not follow Newton's law of viscosity, and...
In contrast, non-Newtonian fluids do not follow Newton's law of viscosity, and...
254