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Updated: Jul 2, 2025

Culture of Murine Embryonic Metatarsals: A Physiological Model of Endochondral Ossification
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Published on: December 3, 2016

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一个合成的,闭环基因电路,用于在体生成过程中自主调节RUNX2活性

Gurcharan Kaur1, Biming Wu1, Sanjana Murali2

  • 1Department of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan, USA.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology
|February 26, 2024
PubMed
概括

设计了一种基因电路来控制RUNX2活动,增强软骨矩阵合成并防止组织工程中的降解. 这种RUNX2抑制策略对治疗退行性关节疾病充满希望.

关键词:
在RUNX2中使用RUNX2.软骨 软骨 软骨是一种人类介质细胞干细胞合成基因电路的合成基因电路

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