相关实验视频

Updated: Jul 2, 2025

Selection-dependent and Independent Generation of CRISPR/Cas9-mediated Gene Knockouts in Mammalian Cells
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Published on: June 16, 2017

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设计抗CRISPR蛋白质,以创建CRISPR-Cas蛋白开关,用于可激活的基因组编辑和病毒蛋白酶检测

Wenyuan Kang1,2, Fei Xiao1, Xi Zhu3

  • 1State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan Provincial Key Laboratory of Biomacromolecular Chemical Biology, Hunan University, Changsha, 410082, P. R. China.

Angewandte Chemie (International ed. in English)
|February 26, 2024
PubMed
概括

研究人员使用抗CRISPR蛋白质设计了合成的CRISPR-Cas开关. 这些开关可以精确控制Cas12a的活动,促进蛋白酶诱导基因组编辑和敏感的病毒诊断.

关键词:
抗克里斯普尔蛋白是一种抗克里斯普尔蛋白.这就是CRISPR-Cas.蛋白质工程是指蛋白质工程.蛋白质开关 开关 开关病毒蛋白酶检测 病毒蛋白酶检测

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