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Andrew Keeler¹, Mathias Lehmann², Jason Luce¹

¹Department of Radiation Oncology, Stritch School of Medicine, Cardinal Bernardin Cancer Center, Loyola University of Chicago, Maywood, Illinois, USA.

Medical physics

|February 26, 2024

概括

双能计算断层扫描 (DE-CT) 成像为放射治疗提供了改善的软组织对比度. 新的TIGRE-DE工具可以在开源平台上进行DE-CT材料分解和虚拟单能图像创建.

科学领域:

医疗成像医学成像
放射治疗物理物理
计算成像技术的成像

背景情况:

双能计算断层扫描 (DE-CBCT) 是一个有前途的成像技术.
它产生虚拟单能 (VM) 图像,具有增强的对比度和减少的工件.
虚拟机图像有助于软组织可视化,用于图像引导放射治疗.

研究的目的:

开发TIGRE-DE,这是DE-CBCT的一个开源模块.
支持DE-CBCT材料分解和VM CBCT图像生成.
增加了DE-CBCT工具的可访问性,用于研究和临床环境.

主要方法:

为TIGRE工具包开发了一个附加模块TIGRE-DE.
在幻影扫描 (80和140kV) 上进行了DE材料分解.
使用FDK算法合成和重建虚拟单能投影.

主要成果:

由TIGRE-DE生成的VM图像与理论Hounsfield单位 (HU) 值有很好的一致性.
测量的HU值在大多数插件中处于临床耐受性范围内 (±50HU).
与传统协议相比,60 keV的VM图像显示了显著的CNR增强 (63-66%).

结论:

TIGRE-DE成功地实现了DE-CBCT材料分解.
该模块有助于创建虚拟单能图像.
为先进的CBCT成像提供了一个可访问的开源解决方案.

关键词:

圆束CT CT 圆束双重能源是什么意思频谱成像技术的使用.

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