临床实践指南:用于吸入物过敏的免疫疗法
Richard K Gurgel1, Fuad M Baroody2, Cecelia C Damask3
1University of Utah, Salt Lake City, Utah, USA.
概括
过敏原免疫疗法 (AIT) 通过诱导耐受性来提供一种管理过敏性鼻炎和喘的方法. 本指南提供基于证据的建议,以确保安全有效的AIT启动和交付,以改善患者护理.
科学领域:
- 过敏和免疫学 过敏和免疫学
- 临床实践指南 临床实践指南
- 免疫治疗是一种免疫疗法.
背景情况:
- 过敏原免疫疗法 (AIT) 是广泛用于过敏性鼻炎 (AR) 和过敏性喘 (AA) 的治疗方法.
- 皮下免疫疗法 (SCIT) 和舌下免疫疗法 (SLIT) 是常见的输送方法.
- 在AIT启动和交付方面存在变化,需要基于证据的建议来提供最佳的患者护理.
研究的目的:
- 确定吸入过敏原免疫疗法 (AIT) 的质量改进机会.
- 为临床医生提供以证据为基础的建议,以AIT管理吸入过敏.
- 为了优化患者护理,促进安全和有效性,减少护理变化,并尽量减少伤害.
主要方法:
- 由指南制定小组 (GDG) 制定临床实践指南 (CPG).
- 专注于基于证据的质量改进机会.
- 基于临床评估,过敏测试和患者因素的建议.
主要成果:
- 强烈建议临床医生在AIT期间诊断和管理过敏反应.
- 建议为不充分控制的AR/AA提供AIT,对SCIT/SLIT进行患者教育,并进行适当的过敏原选择.
- 关于管理局部反应,治疗持续时间和启动AIT的禁忌的指导.
结论:
- 临床医生应为符合条件的AR/AA患者提供AIT.
- 患者教育和对禁忌的仔细评估对于安全有效的AIT至关重要.
- 建议治疗时间至少为3年,以控制症状.
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