在患有状细胞疾病的儿科患者中,复发性非创伤性下血瘤
Irtiza N Sheikh1, Olayinka Okeleji2, Rabya Afzal3
1Division of Pediatrics and Patient Care, Pediatric Stem Cell Transplantation and Cellular Therapy.
Journal of pediatric hematology/oncology
|February 26, 2024
概括
在患有状细胞病 (SCD) 的儿科患者中,自发性状血瘤很少见,但可控. 这种情况模仿中风,但不是致命的,并且可以保守地治疗,没有持久的缺陷.
科学领域:
- 儿科血液学 儿科血液学
- 神经学 神经学
- 血管生物学 血管生物学
背景情况:
- 状细胞疾病 (SCD) 存在缺血性中风的风险.
- 下血瘤是儿科SCD的一个罕见并发症.
- 区分血瘤与中风对于适当的管理至关重要.
研究的目的:
- 在患有SCD的青少年中报告一次复发的SSH病例.
- 突出SSH的保守管理策略.
- 在SCD并发症和治疗的背景下讨论SSH.
主要方法:
- 一个患有SCD的青少年经历了两次SSH和外周血液瘤的病例介绍.
- 对SSH的诊断方法的审查.
- 概述了SSH的保守管理原则.
主要成果:
- 这位患者经历了两年来两个单独的SSH和外周血液瘤发作.
- 第二次发作发生在使用crizanlizumab的治疗期间.
- 保守的管理是成功的,没有焦点神经学缺陷.
结论:
- SSH是一种罕见但在儿科SCD中可管理的疾病.
- SSH诊断和保守治疗对于区分与缺血性中风至关重要.
- 在SCD特定疗法期间对SSH发生的进一步调查可能是有必要的.
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