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Updated: May 5, 2026

Assessment of Mitochondrial Functions and Cell Viability in Renal Cells Overexpressing Protein Kinase C Isozymes
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印-3-碳酸通过通过PKA激活改善线粒体功能障碍,缓解小鼠中西斯普拉丁诱导的急性损伤

Peipei Yuan1, Aozi Feng2, Yaxin Wei3

  • 1Henan University of Chinese Medicine, Zhengzhou, 450046, PR China; Engineering and Technology Center for Chinese Medicine Development of Henan Province, Zhengzhou, 450046, PR China.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
|February 26, 2024
PubMed
概括

印-3-碳酸 (IC) 通过激活PKA和抑制细胞死亡,保护免受西斯胺诱导的损伤. 这项研究表明IC作为减轻化疗相关毒性的潜在治疗剂.

关键词:
急性损伤是什么?急性损伤是什么?西斯普拉丁 (Cisplatin) 是一种印度尔-3-碳酸甲线粒体功能障碍 线粒体功能障碍蛋白激酶A是一种蛋白质激酶.

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Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
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