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使用脂解和透测定方法开发和描述基于固体脂质的利托纳维尔配方 (sLBFs)

Arne Schulzen1, Ioannis I Andreadis2, Christel A S Bergström3

  • 1Institute of Pharmaceutics and Biopharmaceutics, Heinrich Heine University, Universitätsstraße 1, DE-40225, Düsseldorf, Germany.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
|February 26, 2024
PubMed
概括

基于固体脂质的配方 (sLBFs) 显著提高了利托纳维尔的溶解性和透性. 配方成分影响了溶解度,但不影响沉率或透率,突出显示了基于脂质的配方 (LBF) 的结合脂解-透试验的重要性.

关键词:
流量 流量 流量脂质溶解 脂质溶解是一种透透射是一种透的方法.降水量 降水量 降水量基于固体脂质的配方 固体脂质的配方溶解化 溶解化超和 超和 超和

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