身体成分指数与心血管结果的关联:全国性的队列研究
Dongyeop Kim1, Hyung Jun Kim2, Tae-Jin Song1
1Department of Neurology, Seoul Hospital, Ewha Womans University College of Medicine, Seoul, Republic of Korea.
The American journal of clinical nutrition
|February 26, 2024
概括
身体组成,包括瘦身BMI和肌肉质量,对于心血管健康至关重要. 较高的肌肉质量和肌肉质量降低了心血管风险,而较高的身体脂肪增加了心血管风险,BMI类别之间存在差异.
科学领域:
- 心脏病学 心脏病学
- 公共卫生 公共卫生
- 身体组成分析 身体成分分析
背景情况:
- 之前关于身体质量指数 (BMI) 和心血管结果的研究已经产生了相互矛盾的发现.
- 超出BMI的身体成分在心血管风险中的作用需要进一步调查.
研究的目的:
- 检查韩国人群中不同BMI类别内的身体组成指标和心血管结果之间的关联.
- 评估预测的瘦肉BMI (pLBMI),体脂质量指数 (pBFMI) 和尾骨肌质量指数 (pASMMI) 对心血管事件的预测值.
主要方法:
- 一项全国性的队列研究,涉及2,604,401名从国家医疗保险服务-健康检查数据的参与者.
- 使用验证的人类测量方程计算pLBMI,pBFMI和pASMMI.
- 多变量时间依赖的考克斯回归分析以确定BMI类别 (<18.5,18.5-24.9,25-29.9,≥30) 中与心血管结果的关联.
主要成果:
- 较高的pLBMI和pASMMI与男性和女性复合心血管结局风险降低显著相关.
- 较高的pBFMI显着与心血管结果风险增加有关.
- 在体重不足组 (BMI < 18.5) 中,pBFMI与风险的关联不显著,在肥胖组 (BMI ≥ 30) 中,pLBMI和pASMMI的关联不显著.
结论:
- pLBMI,pBFMI和pASMMI是评估心血管风险的有价值指标.
- 这些身体组成指标的预测意义可以根据BMI类别而异.
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