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断绝IFN-γ-依赖的反循环在皮质性关节炎综合征与皮质性和

Wonyong Lee1, Deborah L Stone1, Patrycja Hoffmann1

  • 1Inflammatory Disease Section, National Human Genome Research Institute, Bethesda, Maryland, USA.

Annals of the rheumatic diseases
|February 26, 2024
PubMed
概括

在PSTPIP1中发生的突变会通过激活皮林炎酶激活PAPA综合征,从而导致涉及IL-18和IFN-γ的积极反循环. 雅克抑制剂在治疗这种自身炎症性疾病方面表现有前途.

关键词:
关节炎是一种关节炎.细胞因子 (cytokines) 是一种细胞因子.家庭地中海热病家族性地中海热炎症 炎症是一种炎症.

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