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Updated: Jul 2, 2025

Genome-wide Purification of Extrachromosomal Circular DNA from Eukaryotic Cells
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Published on: April 4, 2016

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scCircle-seq揭示了单细胞中染色体外圆形DNA的多样性和复杂性

Jinxin Phaedo Chen1,2, Constantin Diekmann3,4, Honggui Wu5,6

  • 1Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, 17177, Sweden. jinxin.chen@ki.se.

Nature communications
|February 26, 2024
PubMed
概括

异染色体圆形DNA (eccDNA) 的单细胞测序揭示了它们在细胞调节和癌症中的多样性作用. 这种名为scCircle-seq的新方法表明,eccDNA在细胞之间存在差异,可以作为癌症生物标志物.

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