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肠层通过GM-CSF引导单细胞分化到巨细胞

Egle Kvedaraite1,2,3, Magda Lourda4,5, Natalia Mouratidou6,7

  • 1Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden. egle.kvedaraite@ki.se.

Nature communications
|February 26, 2024
PubMed
概括

流体细胞,特别是PDGFRA+CD142-/低纤维细胞,在儿科炎性肠病 (IBD) 中引导单细胞分化为巨细胞. 这种由GM-CSF调解的相互作用会影响炎症肠道中的巨细胞表型.

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