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Updated: Jul 2, 2025

Bacterial Leaf Infiltration Assay for Fine Characterization of Plant Defense Responses using the Arabidopsis thaliana-Pseudomonas syringae Pathosystem
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通过ADH5维持的S-nitrosothiol稳态促进了对病原体的STING-依赖宿主防御

Mutian Jia1,2, Li Chai1,2, Jie Wang1,2

  • 1Department of Pathogenic Biology, Key Laboratory for Experimental Teratology of the Chinese Ministry of Education, and Key Laboratory of Infection and Immunity of Shandong Province, School of Basic Medical Science, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China.

Nature communications
|February 26, 2024
PubMed
概括

在氧化突发过程中产生的反应性物种 (RNS) 可以通过积累S-nitrosothiols (SNOs) 损害先天免疫力. 酒精脱酶5 (ADH5) 通过代谢SNO来帮助维持免疫反应,从而授权STING激活.

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