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可能的萨尔科佩尼亚对急性中风患者的功能预后的影响,先发性残疾

Tomoyuki Ogino¹, Masafumi Nozoe², Tatsuro Inoue³

¹Department of Physical Therapy, School of Rehabilitation, Hyogo Medical University, Kobe, Japan.

Geriatrics & gerontology international

|February 27, 2024

Aim:

尚不清楚可能的肌少症对发病前存在功能障碍患者的临床功能预后有何影响。本研究旨在比较并探讨急性卒中患者在入院时存在可能的肌少症对其出院时功能结局的影响，特别分析有无发病前功能障碍的患者之间的差异。

方法:

本队列研究连续纳入了一家医疗中心收治的急性卒中患者。在入院后7天内测量患者的小腿围和握力，并依据2019年亚洲肌少症工作组标准判定是否存在可能的肌少症。研究的主要结局指标为急性期出院时的功能独立性评定量表（Functional Independence Measure, FIM）评分。为探讨可能的肌少症对出院时FIM评分的影响，根据改良Rankin量表评估结果将患者分为有或无发病前功能障碍的两组，并在每组中分别进行多重线性回归分析。

结果:

本研究纳入了456例急性卒中患者（中位年龄80岁）。在发病前存在残疾的患者组（n = 166）中，140例（84%）存在可能的少肌症。与存在可能少肌症的患者相比，无可能少肌症的患者出院时FIM评分显著更高（P < 0.001）。然而，多元线性回归分析显示，在发病前存在残疾的患者组中，可能的少肌症与出院时FIM评分无显著关联（β = -0.054，P = 0.346）。

结论:

本研究结果显示，发病前存在功能障碍的卒中患者中，可能患有肌少症的比例较高；然而，这并未影响其功能预后。Geriatr Gerontol Int 2024; 24: 359-363.

关键词:

剧烈的中风是急性中风.功能预后功能预后可能的萨尔科佩尼亚.患病前的残疾.

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