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在接受免疫抑制关节镜术的风湿病患者的术后并发症
Kinjal Vasavada1, Charles C Lin2, Laith M Jazrawi3
1Division of Sports Medicine, Department of Orthopaedic Surgery, New York University Langone Orthopedic Center, New York, NY, USA.
The Physician and sportsmedicine
|February 27, 2024
概括
对于接受关节镜检查的类风湿病患者来说,在外科手术期间持续免疫抑制 (IS) 治疗具有较低的术后并发症风险. 这项研究发现,在继续,保持或不接受IS治疗的患者之间,感染率没有显著差异.
科学领域:
- 整形外科手术 整形外科手术
- 类风湿病学 类风湿病学
- 药理学 药理学是指药理学的学科.
背景情况:
- 缺乏建立的指导方针,管理免疫抑制 (IS) 治疗在经过关节镜手术的类风湿病患者.
- 需要基于证据的建议,以优化术后护理.
研究的目的:
- 描述经过关节镜检查的类风湿病患者.
- 根据外科手术期间的IS管理 (持续,持续或不持续) 来比较术后并发症率.
- 根据类型的风湿性疾病,药物和手术风险分析并发症.
主要方法:
- 在11年内对1316名类风湿病患者进行了回顾性审查.
- 分类为三个组:持续的IS,持有IS,或在基线没有IS.
- 统计分析 (ANOVA,奇平方,费舍尔精确测试) 以比较并发症发生率.
主要成果:
- 214名患者接受了IS治疗,110人继续接受治疗,104人接受治疗,1102人没有接受IS治疗.
- 七名患者出现了术后并发症 (六例感染).
- 在三个IS管理组中,并发症或感染率没有统计学上显著的差异.
结论:
- 在接受关节镜检查的类风湿病患者中,外科术期间的免疫抑制治疗与低且可接受的并发症风险有关.
- 目前的管理策略似乎是安全的,在继续IS治疗的患者中没有观察到增加的风险.
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