Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Factors Affecting Renal Clearance: Renal Impairment01:17

Factors Affecting Renal Clearance: Renal Impairment

94
Renal dysfunction significantly impairs the renal clearance of drugs, leading to potential complications in drug therapy. Renal failure, which can be caused by various factors, poses a significant challenge in the elimination of drugs from the body.
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
94
Renal Clearance01:23

Renal Clearance

935
The glomerular filtration rate (GFR) is a critical marker of kidney function, reflecting the efficiency of filtration by the glomeruli. Renal clearance of specific substances, such as inulin or creatinine, is commonly used to measure GFR.
Renal clearance refers to the volume of plasma cleared of a specific substance, such as creatinine, per unit of time. To measure clearance, urine samples are collected over a 24-hour period during each bladder voiding, followed by a single blood sample at the...
935

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Beyond consent: community engagement, benefit sharing and reciprocity in kidney genomics research.

Nature reviews. Nephrology·2026
Same author

Advances in the diagnosis and detection of chronic kidney disease.

Lancet (London, England)·2026
Same author

Advances in understanding the impact of sex on kidney health and disease.

Lancet (London, England)·2026
Same author

Chronic kidney disease, complex conditions, and advancing therapeutics: new hope and challenges.

Lancet (London, England)·2026
Same author

Hypertension Incidence and Its Risk Factors in a Longitudinal Cohort of Middle-Aged Men and Women Living in Urban South Africa.

Journal of clinical hypertension (Greenwich, Conn.)·2026
Same author

Multinational validation of the PREVENT and SCORE2 cardiovascular risk equations across 6.4 million individuals.

Nature medicine·2026

相关实验视频

Updated: Jul 2, 2025

Cytosolic Calcium Measurements in Renal Epithelial Cells by Flow Cytometry
10:24

Cytosolic Calcium Measurements in Renal Epithelial Cells by Flow Cytometry

Published on: October 28, 2014

15.3K

囊素C应该经常可用于估计功能.

Jennifer S Lees1, June Fabian2, Michael G Shlipak3

  • 1School of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow, UK.

Current opinion in nephrology and hypertension
|February 27, 2024
PubMed
概括

囊素C测试比肌素更准确地评估功能,特别是在脆弱人群中. 科医生的早期采用可以改善患者的治疗结果,并减少医疗保健差异.

科学领域:

  • 腎臟病學 (nephrology) 是一種醫學專業.

更多相关视频

Implementing Patch Clamp and Live Fluorescence Microscopy to Monitor Functional Properties of Freshly Isolated PKD Epithelium
08:46

Implementing Patch Clamp and Live Fluorescence Microscopy to Monitor Functional Properties of Freshly Isolated PKD Epithelium

Published on: September 1, 2015

9.8K
The Importance of Correct Protein Concentration for Kinetics and Affinity Determination in Structure-function Analysis
19:16

The Importance of Correct Protein Concentration for Kinetics and Affinity Determination in Structure-function Analysis

Published on: March 17, 2010

20.6K

相关实验视频

Last Updated: Jul 2, 2025

Cytosolic Calcium Measurements in Renal Epithelial Cells by Flow Cytometry
10:24

Cytosolic Calcium Measurements in Renal Epithelial Cells by Flow Cytometry

Published on: October 28, 2014

15.3K
Implementing Patch Clamp and Live Fluorescence Microscopy to Monitor Functional Properties of Freshly Isolated PKD Epithelium
08:46

Implementing Patch Clamp and Live Fluorescence Microscopy to Monitor Functional Properties of Freshly Isolated PKD Epithelium

Published on: September 1, 2015

9.8K
The Importance of Correct Protein Concentration for Kinetics and Affinity Determination in Structure-function Analysis
19:16

The Importance of Correct Protein Concentration for Kinetics and Affinity Determination in Structure-function Analysis

Published on: March 17, 2010

20.6K
  • 临床化学 临床化学
  • 生物标记分析 生物标记分析

    • 背景情况:

    • 基于肌素的估计膜过率 (eGFRcr) 有局限性,导致至少25%的个体存在显著差异 (eGFRdiff).
    • 这些差异在老年人,女性,非白人和患有并发病的人群中更为普遍,影响了诊断和治疗.
    • 与eGFRcr (大型eGFRdiff) 相比,较低的eGFRcys与急性损伤,心血管疾病,衰竭和死亡率等不良结果有关.

    结论:

    • 与肌素相比,Cystatin C可以更准确地估计膜过率 (GFR),特别是在存在差异的情况下.
    • 由教育和动机驱动的脏病学家越来越多地采用囊素C检测,可以显著改善患者的护理.
    • 使用囊素C可以导致更好地管理病,改善患者安全,并减少健康差异.