关于间歇性肺病和类风湿性关节炎其他选定的关节外表现的最新信息
Elena Myasoedova1, Eric L Matteson
1Division of Rheumatology, Mayo Clinic College of Medicine and Science, Rochester, Minnesota, USA.
Current opinion in rheumatology
|February 27, 2024
概括
由于更好的治疗方法,类风湿性关节炎 (ExRA) 的关节外表现正在下降. 然而,类风湿性关节炎相关的间歇性肺病 (RA-ILD) 仍然是一个具有有限选择的挑战.
科学领域:
- 风湿病学和免疫学
- 自身免疫性疾病的流行病学
背景情况:
- 类风湿性关节炎 (RA) 的关节外表现 (ExRA) 正在下降,特别是皮下类风湿性结节.
- 与RA相关的间歇性肺病 (RA-ILD) 发病率保持不变,并构成显著的死亡风险.
- 在RA中心血管疾病的风险通常是可以管理的,但与JAK抑制剂相关的风险需要进一步了解.
结论:
- 虽然整体ExRA发病率下降,但RA-ILD仍然是一个关键的治疗挑战.
- 新型抗纤维素和免疫抑制药物有可能减缓RA-ILD的进展.
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