强电荷转移等离子体在金色纳米粒子二极体中,由导电分子链接器连接在一起
A S Fedorov1,2, M A Visotin1,3, A V Lukyanenko1,3
1Kirensky Institute of Physics, Federal Research Center KSC SB RAS, 660036 Krasnoyarsk, Russia.
The Journal of chemical physics
|February 27, 2024
概括
研究人员合成了由分子连接的金纳米粒子二极体,创建了一个电荷转移等离子体 (CTP) 模式. 这种CTP模式显示近红外吸收,使瘤的高温治疗成为可能.
科学领域:
- 纳米技术 纳米技术
- 塑制剂的使用方法
- 生物医学工程 生物医学工程
背景情况:
- 金纳米粒子表现出局部化的等离子体共振.
- 分子连接器可以跨越纳米粒子,从而可能实现新的光学特性.
- 由于组织透明度,近红外吸收对于生物医学应用是理想的.
研究的目的:
- 合成和表征金纳米粒子二次体,由1,2-bis(2-pyridyl) 乙烯连接在一起.
- 为了研究这些二极体中的光学特性和电荷转移.
- 评估这些二极体在生物医学应用中的潜力,特别是高温症.
主要方法:
- 金纳米粒子二次体的合成.
- 传输电子微摄影用于结构确认.
- 密度函数理论计算用于电荷转移分析.
- 紫外线-Vis光谱法用于确定光学特性.
- 在体外激光照射用于高热度评估.
主要成果:
- 稳定的金纳米粒子二次体 (22纳米直径) 已成功生产出来.
- 通过分子链接器的电荷转移在理论上得到了证实.
- 观察到一个新的吸收峰值在780nm,归因于电荷转移等离子体 (CTP) 模式.
- 实验频谱与CTP模型保持一致.
- 在体外加热CTP二元溶液时,使用792nm激光达到6°C,足以引起高温症.
结论:
- 合成的金纳米粒子二极管表现出带电转移等离子体 (CTP) 模式,具有近红外吸收.
- 这种CTP模式的吸收处于生物组织传播窗口内.
- 二度体显示出高效的体外加热,显示出高温治疗癌症的潜力.
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