口腔状细胞癌的预后风险因素:一个病例对照研究
Jacquelyn K Callander1, Spenser S Souza1, Yasmin Eltawil2
1Department of Otolaryngology-Head and Neck Surgery, University of California-San Francisco, San Francisco, California, USA.
Head & neck
|February 27, 2024
概括
口腔状细胞癌 (SCC) 与其他口腔状细胞癌具有相似的生存结果,尽管它呈现在更高的T阶段. 65岁以上的年龄,围神经侵袭和正边缘是口腔SCC复发和死亡的关键风险因素.
科学领域:
- 在瘤学瘤学.
- 头部和部手术 头部和部手术
- 口腔病理学 口腔病理学
背景情况:
- 口腔状细胞癌 (SCC) 是口腔状细胞癌 (OCSCC) 的一个子集.
- 了解其独特的临床病理特征和风险因素对于有效管理至关重要.
研究的目的:
- 为了划分口腔SCC的临床病理表现.
- 确定与口腔SCC患者复发和整体生存相关的特定风险因素.
主要方法:
- 一个单一的三级保健中心的回顾性病例控制研究 (2010-2022年).
- 包括77名口腔SCC患者与77名非口腔OCSCC对照匹配.
- 通过图表审查收集的数据.
主要成果:
- 口腔SCC患者的年龄和性别分布与对照组相似.
- 复发率相似 (26%的口腔与25%的非口腔).
- 年龄≥65岁,围神经侵袭和正边缘增加了口腔SCC的死亡率/复发率.
- 总体和无进展生存时间在各组之间没有显著差异.
结论:
- 与其他OCSCC子站点相比,口腔SCC通常呈现在更高的T阶段.
- 不良结果的病理风险因素在口腔和非口腔OCSCC之间可能有所不同.
- 尽管呈现方式有差异,但口腔和非口腔OCSCC之间的瘤结果仍然相似.
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