从2004年至2020年对T1状状细胞癌的护理模式
Devesh Malik1, Daniel Jacobs2, Soraya Fereydooni1
1Yale University School of Medicine, New Haven, Connecticut, USA.
The Laryngoscope
|February 27, 2024
概括
对T1喉状状细胞癌 (SCC) 的过度治疗率正在下降,只有手术治疗方法的增加. 治疗年和瘤阶段 (T1b与T1a) 影响了治疗选择.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 头部和部手术 头部和部手术
- 癌症治疗研究 癌症治疗研究
背景情况:
- 状状细胞癌 (SCC) 是一种常见的头癌.
- 早期喉SCC (T1) 的治疗方法包括放射治疗 (RT) 和手术.
- 了解国家治疗趋势对于优化患者护理至关重要.
研究的目的:
- 分析T1喉SCC治疗方式的最近的国家趋势.
- 确定与不同治疗方案相关的因素,包括手术,RT和双模治疗.
- 评估变化的情况.
- 过度处理过度处理
- 利率随着时间的推移.
主要方法:
- 利用国家癌症数据库 (2004-2020年) 对患有喉cT1N0M0 SCC的患者.
- 使用Cochran-Armitage测试来分析治疗模式的趋势.
- 进行多变量逻辑回归以确定与治疗选择相关的因素.
主要成果:
- 大多数患者 (57%) 仅接受RT,21%仅接受手术,22%接受双模治疗.
- 观察到双模治疗 ("过度治疗") 的显著下降趋势 (p < 0.001).
- 仅进行手术治疗的趋势有所增加 (p < 0.001).
- 较早的治疗年与过度治疗的可能性更高有关.
- 与T1a瘤相比,T1b瘤不太可能过度治疗,也不太可能首先接受手术.
结论:
- 对T1喉SCC的双模治疗减少了,同时单模手术的增加.
- 治疗一年对接受双种治疗方式的可能性产生重大影响.
- T1b瘤倾向于RT作为主要和唯一的治疗方式.
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