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Updated: Jul 2, 2025

Defining Hsp33's Redox-regulated Chaperone Activity and Mapping Conformational Changes on Hsp33 Using Hydrogen-deuterium Exchange Mass Spectrometry
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Defining Hsp33's Redox-regulated Chaperone Activity and Mapping Conformational Changes on Hsp33 Using Hydrogen-deuterium Exchange Mass Spectrometry

Published on: June 7, 2018

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氧化应激诱导人血清白蛋白的形状变化

Debdip Brahma1, Akshay Narayan Sarangi1, Rupal Kaushik1

  • 1Biophysics and Soft Matter Laboratory, Department of Physics, Indian Institute of Technology, Kharagpur, 721302, India. ang@phy.iitkgp.ac.in.

Physical chemistry chemical physics : PCCP
|February 27, 2024
PubMed
概括

反应性氧物种 (ROS) 引起氧化应激,损害像人血清白蛋白 (HSA) 这样的蛋白质. 这项研究揭示了ROS诱导的氧化如何导致HSA展开和聚合,影响其结构和功能.

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