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在心律失常的右心室心肌病症中,右心房菌株的预后值

Jin-Yu Zheng¹, Bing-Hua Chen¹, Rui Wu¹

¹Department of Radiology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200127, People's Republic of China.

Insights into imaging

|February 27, 2024

概括

右心房应变参数,包括储应变 (RARS) 和助推应变 (RABS),是心律失常性右心室心肌病 (ARVC) 中心脏不良事件的独立预测因素. 这些措施为ARVC患者提供了超越传统风险因素的增量预后价值.

科学领域:

心脏病学心脏病学
心血管成像 - 心血管成像
遗传学遗传学是一个

背景情况:

节律失调的右室心肌病变 (ARVC) 是一种遗传性心脏病.
心脏肌肉的纤维脂肪透导致不良心脏事件.
人们越来越认识到右心房 (RA) 功能对预后的重要性.

研究的目的:

在ARVC患者中分析右心房 (RA) 应变的预后值.
为了确定RA菌株参数是否可以预测ARVC中的不良心脏事件.
评估RA菌株的增量预测能力.

主要方法:

用心磁共振成像 (CMR) 评估了105名ARVC参与者的RA菌株.
不良心脏事件被定义为心脏突然死亡,心脏骤停或适当的ICD干预.
考克斯回归和卡普兰-梅尔分析评估了RA菌株和终点之间的关联,C指数,NRI和IDI评估了增量值.

主要成果:

在经历不良事件的患者中观察到减少了RA菌株参数.
损伤的RA储菌株 (RARS) 和助推菌株 (RABS) 与心脏事件的更高风险有关.
RARS和RABS独立预测了不良事件,改善了传统的风险因素和CMR预测器.

结论:

在ARVC中,RA储菌株 (RARS) 和助推菌株 (RABS) 是心脏不良事件的独立预测因素.
这些RA菌株参数提供了显著的增量预后价值.
心脏病专家应考虑RA菌株评估,以便在ARVC中更好地预测长期结果和临床管理.

关键词:

节律失常性右心室心肌病变性 - 右心室心肌病变性节律失常的右心室发育不良症.磁共振成像技术磁共振成像技术右心房的功能是正确的压力应变是一种压力.

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