Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关实验视频

Danielle M Martindale1, Jenica L Haraschak1, Andrew J Thiel2

  • 1Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois, Urbana, Illinois, USA.

Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)
|February 27, 2024
PubMed
概括
此摘要是机器生成的。

这份病例报告详细介绍了一只狗的致死性lisdexamfetamine dimesylate (LDX) 毒性,强调了尽管迅速治疗,但严重的全身效应. 它强调了在胺毒性病例中需要预后指标的需要.

关键词:
胺类药物和胺类药物.注意缺陷/多动症障碍注意力缺陷/多动症障碍狗类犬类动物 狗类犬类心血管毒性心血管毒性神经毒性的作用.拉布多米溶解 (rhabdomyolysis) 是一种治疗方法.

相关实验视频

相关概念视频

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

EXPRESS: Ala vestibuloplasty for treatment of feline brachycephalic syndrome: a description of the procedure and long-term outcomes in 27 cats.

Journal of feline medicine and surgery·2026
Same author

Analysis of persistent organic pollutants (organochlorine pesticides & PCBs) in livers of leatherback sea turtles (<i>Dermochelys coriacea</i>) by GC-MS/MS.

Toxicology mechanisms and methods·2026
Same author

Characterization of unusual immunoassay cross-reactive cannabinoid metabolites in canine urine via gas chromatography-mass spectrometry.

Toxicology mechanisms and methods·2026
Same author

Anemia and icterus in 2 mixed-breed sheep.

Journal of the American Veterinary Medical Association·2026
Same author

Pharmacokinetics and pharmacodynamics of desoxycorticosterone pivalate in dogs with hypoadrenocorticism.

Journal of veterinary internal medicine·2026
Same author

Evaluation of the Use of a Medium Cut-Off Dialyser Theranova 400 for Severe Metaldehyde Intoxication in Three Dogs: Dialytic Clearance and Therapeutic Response.

Veterinary medicine and science·2026
Same journal

Teaching Clinical Competency: Evaluating POCUS-Guided Versus Landmark Techniques for Thoracostomy Tube Placement in Canine Cadavers by Veterinary Students.

Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)·2026
Same journal

Utility of Cytology of Spontaneously Expectorated Sputum Samples in the Diagnosis of Blastomycosis in Dogs.

Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)·2026
Same journal

Evaluation of Point-of-Care Coagulation Measurement Systems for Activated Clotting Time and Partial Thromboplastin Time in Heparinized and Non-Heparinized Equine Blood.

Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)·2026
Same journal

Multi-Institutional, Retrospective Evaluation of Risk Factors Predicting Complications Associated With Perineal Urethrostomy in Cats With Urethral Obstruction (2009-2019): 140 Cases.

Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)·2026
Same journal

Retrospective Report of Improvement Following Treatment With Intravenous Lipid Emulsion Therapy in Two Puppies With Hyperammonemia and Signs of Hepatic Encephalopathy Refractory to Conventional Therapy.

Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)·2026
Same journal

Hypoventilation After Placement of an External Splint in a Cat With Severe Pectus Excavatum Managed With Pressure Support Ventilation.

Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)·2026
查看所有相关文章

科学领域:

  • 兽医毒理学 兽医毒理学
  • 狗类药理学 狗类药理学
  • 紧急医疗 紧急医疗

背景情况:

  • 利斯德胺二酸盐 (LDX) 是一种兴奋剂药物.
  • 意外摄入可导致狗的毒性病变.
  • 关于犬类严重LDX毒性结局的数据有限.

研究的目的:

  • 为了记录狗的LDX毒性病的临床表现.
  • 描述管理和死后发现.
  • 为了突出严重的,致命的结局,尽管治疗.

主要方法:

  • 一个3岁的雌性狗被怀疑患有LDX毒性病的案例报告.
  • 典型的安非他胺毒性症的治疗方法.
  • 尽管在重症监护室,心肺骤停发生.
  • 尸检和毒理学证实了LDX和安非他胺.

主要成果:

  • 神经症状进展为严重的呼吸和心血管损害.
  • 这只狗经历了心肺骤停,无法复活.
  • 尸体检查显示有大量出血.
  • 毒理学证实了lisdexamfetamine二甲酸和安非他胺.

结论:

  • 这是首次报告证实,严重的,致命的LDX毒性在狗.
  • 在这种严重的病例中,迅速治疗并不能预防死亡.
  • 表明需要确定安非他胺毒性病的负面预后指标.
  • 用了一种新的毒理学分析技术来证实在狗身上.