在Covid-19期间对耳膜炎的临床观察
Xiuni Liang1, Bei Zhang, Ying Ding
1Division of Otolaryngology, Department of Surgery, Head and Neck Surgery, The University of Hong Kong-Shenzhen Hospital, Shenzhen 518000, PR China.
在Omicron变种大流行期间,耳膜炎媒介分泌量增加了15%,感染在2022年12月下旬达到峰值. SARS-CoV-2 病毒可以在中耳液中持续存在,这表明中耳可能存活更长时间.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 传染性疾病 传染性疾病
- 病毒学 病毒学
背景情况:
- 耳膜炎是病毒感染后的一个常见并发症.
- SARS-CoV-2的Omicron菌株已经表现出各种临床表现和并发症.
- 了解病毒在不同身体部位的持久性对于管理感染后的后果至关重要.
研究的目的:
- 在SARS-CoV-2 Omicron菌株大流行期间分析耳膜炎的发病率和发病时间.
- 为了调查中耳腔中SARS-CoV-2的存在和生存时间.
- 评估一种用于检测中耳溢液中SARS-CoV-2抗原的新方法.
主要方法:
- 在感染Omicron菌株期间与非感染期间对中耳炎分泌发生率的回顾性比较.
- 使用问卷和星级应用程序收集人口和流行病学数据.
- 采用了一种新的SARS-CoV-2抗原检测套件 (合金法) 来进行中耳溢液分析.
主要成果:
- 在Omicron大流行期间,中耳炎分泌发生率增加了15%.
- SARS-CoV-2 Omicron感染的峰值发生在2022年12月15日至25日左右,感染后7-9天的峰值传播.
- 在12%的中耳液中检测到SARS-CoV-2抗原;负面病例显示疾病持续时间超过3周.
结论:
- 中耳膜炎是Omicron菌株SARS-CoV-2感染的常见并发症,与中耳病毒存在有关.
- 与鼻腔相比,SARS-CoV-2病毒在中耳溢液中表现出更长的存活时间.
- 中耳溢出检测可以检测SARS-CoV-2抗原和残留病毒的存在.
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