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Updated: Jul 2, 2025

CRISPR-Mediated Reorganization of Chromatin Loop Structure
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Published on: September 14, 2018

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通过与R循环的直接相互作用,LC3B驱动了与转录相关的同源重组

Junghyun Yoon1,2, Yiseul Hwang1,2, Hansol Yun1,2

  • 1Department of Physiology, Ajou University School of Medicine, Suwon, Gyeonggi 16499, Republic of Korea.

Nucleic acids research
|February 27, 2024
PubMed
概括

LC3B蛋白对于DNA修复至关重要,促进转录相关同源重组 (TA-HRR) 独立于自. 它与DNA病变和BRCA1相互作用,通过防止转移到易发生错误的途径来确保基因组稳定性.

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