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Updated: Jul 2, 2025

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核糖体质量控制因子抑制来自GC丰富重复的重复关联非AUG转化

Yi-Ju Tseng1,2, Amy Krans1,3, Indranil Malik1,4

  • 1Department of Neurology, University of Michigan, Ann Arbor, MI 48109, USA.

Nucleic acids research
|February 27, 2024
PubMed
概括

核糖体质量控制因素限制了重复扩张障碍的有毒蛋白质生产,如ALS和FTD. 增强这些因素可能为这些神经退行性疾病提供治疗策略.

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