狗结核病:对18例新的确诊病例和565例之前报告的确诊病例进行了审查
Conor O'Halloran1, Emi N Barker2, Jayne C Hope1
1Royal (Dick) School of Veterinary Studies and The Roslin Institute, University of Edinburgh, Easter Bush Campus, Midlothian, EH25 9RG United Kingdom.
Veterinary journal (London, England : 1997)
|February 27, 2024
概括
狗结核病是一种动物传播疾病,很少报告. 这项研究审查了583个病例,确定了Mycobacterium microti作为英国的原因,并发现了抗菌药物治疗的成功治疗结果.
科学领域:
- 兽医医学 兽医医学 兽医医学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 狗结核病 (TB) 是一种带有重大公共卫生影响的动物感染,尽管病例很少被记录.
- 狗的结核菌菌复合体 (MTBC) 感染存在诊断和临床挑战.
研究的目的:
- 收集和分析感染Mycobacterium tuberculosis-complex (MTBC) 的狗的病例细节.
- 描述犬类结核病的临床表现和结果.
- 为了确定涉及到犬类感染的MTBC物种.
主要方法:
- 观察性研究,结合了回顾性和前性数据.
- 审查了583个确认的犬类结核病例 (18个新病例,565个历史病例).
- 诊断技术包括培养,干扰素释放试验 (IGRA) 和PCR.
主要成果:
- 所有确定的病例都是由M. tuberculosis,M. bovis或M. microti引起的.
- 这项研究报告了英国第一个犬类M. microti感染.
- 临床表现包括肺部 (44.1%),腹部 (14.5%),传播和各种形式.
- 在接受治疗的92%的狗中,三重抗菌疗法是成功的.
结论:
- 开发辅助诊断测试对于及时的治疗决定至关重要,因为MTBC培养需要数周到数月.
- 三重抗菌药物治疗显示出高成功率, 92%的治疗犬获得了良好的临床结果.
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