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Updated: Jul 2, 2025

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NFIL3有助于细胞毒性T淋巴细胞介导的杀死

Tiphaine Douanne1, Katharina Strege1,2, Martin Del Castillo Velasco-Herrera2

  • 1Cambridge Institute for Medical Research, Keith Peters Building, Cambridge CB2 0XY, UK.

Open biology
|February 27, 2024
PubMed
概括

核因子IL-3 (NFIL3) 对细胞毒性T淋巴细胞 (CTL) 功能至关重要. 删除NFIL3会通过影响细胞分解蛋白质的产生,而不是信号通路,损害CTL细胞毒性.

关键词:
在 NFIL3 中.通过T细胞媒介的杀死.这是自身免疫力.细胞毒性T细胞细胞毒性一个叫做granzyme的大酶.穿孔是为了穿孔.

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