在精神分裂症中减弱的动机:从社会场景中基于努力的新型决策任务中得到的证据
Yu-Xin Shao1,2,3, Ling-Ling Wang4, Han-Yu Zhou5
1Key Laboratory of Brain Functional Genomics (MOE and STCSM), Affiliated Mental Health Center (ECNU), School of Psychology and Cognitive Science, East China Normal University, Room 413, Building Junxiu, 3663 North Zhongshan Road, Shanghai, 200062, China.
European archives of psychiatry and clinical neuroscience
|February 27, 2024
概括
精神分裂症 (SCZ) 患者由于冷漠,在社交场合所做的努力减少. 这影响了他们追求需要社会参与的工作的意愿,突出了临床干预的关键领域.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 行为经济学是一种行为经济学.
背景情况:
- 漠不关心是精神分裂症 (SCZ) 的核心负面症状,显著影响社会功能.
- 在SCZ患者中,动机缺陷在社会决策中的确切作用仍未得到充分研究.
研究的目的:
- 在SCZ患者的社会背景下研究基于努力的决策.
- 检查SCZ中冷漠程度与社会努力分配之间的关系.
主要方法:
- 开发了模拟工作面试任务,以评估社会场景中的基于努力的决策.
- 为主要研究招募了45名SCZ患者和49名健康对照 (HC).
- 测量硬任务选择比例和主观评分来比较群体.
主要成果:
- 与HC相比,SCZ患者的艰难任务选择减少了,特别是对于严格采访者的中高奖励值.
- 较大的冷漠程度与选择艰难任务的可能性较低相关.
- 患有SCZ的患者表现出不太愿意为要求更高社会参与度的工作而付出努力.
结论:
- 在SCZ中受损的基于努力的决策延伸到社会和生态相关的环境中.
- 异常的努力分配与精神分裂症的负面症状密切相关.
- 调查结果可能有助于制定针对SCZ的有针对性的干预措施.
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