在患有阻塞性睡眠呼吸暂停-睡眠暂停综合征的患者中,隔膜功能的超声波变化和影响因素
Zhijun Wang1, Jing Li2, Yingchun Zhang2
1Department of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Soochow University, 1055 Sanxiang Road, Suzhou, Jiangsu, China.
Sleep & breathing = Schlaf & Atmung
|February 27, 2024
概括
隔膜功能障碍,包括厚度和收缩能力降低,在阻塞性睡眠呼吸暂停-催眠症综合征 (OSAHS) 中显而易见. 夜间间歇性缺氧被确定为OSAHS患者这些隔膜变化的关键风险因素.
科学领域:
- 肺部医学 肺部医学
- 睡眠医学 睡眠医学
- 诊断成像 诊断成像 诊断成像
背景情况:
- 阻塞性睡眠呼吸暂停-呼吸暂停综合征 (OSAHS) 与隔膜功能障碍有关.
- 在OSAHS中导致隔膜功能障碍的危险因素尚不清楚.
- 超声波提供了一种非侵入性方法来评估隔膜功能.
研究的目的:
- 为了评估OSAHS患者的隔膜功能.
- 确定影响OSAHS患者腹膜超声波变化的因素.
主要方法:
- 一项涉及150名打患者的横截面研究,根据呼吸暂停-呼吸暂停指数 (AHI) 将他们分为控制,轻度至中度OSAHS和严重OSAHS组.
- 通过2D超声波测量功能残余容量 (TFRC) 和肺总容量 (TTLC) 的隔膜厚度.
- 使用M模式超声波评估潮和深呼吸期间的隔膜外流;计算隔膜加厚分数 (TF).
- 斯皮尔曼分析和多重线性渐进回归用于确定冲击因子.
主要成果:
- 在TFRC,TTLC和TF的显著差异被观察到跨组 (P <0.05).
- 氧气脱度指数 (ODI) 被确定为TFRC,TTLC和TF (P <0.05) 的重要影响因素.
- 隔膜厚度增加,而收缩性 (TF) 随着OSAHS的严重程度而下降.
结论:
- 在OSAHS患者中存在隔膜缩和受损收缩能力.
- 夜间间歇性缺氧,以ODI表示,是OSAHS中腹膜功能障碍的危险因素.
- 超声波评估为OSAHS的隔膜变化提供了有价值的见解.
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