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Updated: Jul 2, 2025

Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
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中性细胞-骨质细胞轴在牙周炎中促进骨破坏

Yutaro Ando1,2,3, Masayuki Tsukasaki4, Nam Cong-Nhat Huynh1,5

  • 1Department of Immunology, Graduate School of Medicine and Faculty of Medicine, The University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, Tokyo, Japan.

International journal of oral science
|February 27, 2024
PubMed
概括

中性粒细胞通过释放上素M (OSM) 来驱动牙周炎的骨质损失,这刺激骨质细胞产生RANKL. 针对这种OSM-RANKL通路可以减少骨损伤,为这种常见的牙疾病提供新的治疗策略.

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