隔离性心房隔膜缺陷的危险因素第二发病率
Gustaf Tanghöj1, Estelle Naumburg2
1Unit of Pediatrics, Department of Clinical Sciences, Umeå University, Umeå, Sweden.
Scientific reports
|February 27, 2024
概括
在患有隔离性心房隔膜缺陷 (ASD II) 的儿童中,早产并不是心脏问题的危险因素. 然而,唐氏综合征与这些儿童心脏病发病率的增加有关.
科学领域:
- 儿科 儿科 儿科
- 心脏病学 心脏病学
- 遗传性心脏缺陷 遗传性心脏缺陷
背景情况:
- 心房隔膜缺陷第二 (ASD II) 是一种常见的先天性心脏缺陷,特别是在早产婴儿中.
- 了解ASDII儿童心脏病发病的风险因素对于有效管理至关重要.
研究的目的:
- 调查早产是否与被诊断为孤立的ASD II的儿童心脏病发病率增加有关.
- 在这个儿科群体中确定心脏病发病的独立风险因素.
主要方法:
- 基于国家注册的回顾性病例控制研究.
- 在瑞典出生 (2010-2015年) 患有孤立自闭症的儿童的纳入 II.
- 有条件的物流回归分析,对混因素进行调整.
主要成果:
- 11%的孤立ASDII儿童需要治疗心力衰竭.
- 唐氏综合征被确定为心脏病发病的唯一独立风险因素 (OR = 2.25).
- 过早分娩与孤立的ASD II.儿童心脏病发病率的增加没有显著关联.
结论:
- 过早分娩似乎不是孤立的ASD II.儿童心脏病发病的独立风险因素.
- 唐氏综合征是患有ASD II的儿童心脏病发病的重要危险因素.
- 进一步的研究可能会探索在这个群体中对心脏病发病的其他潜在因素.
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