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Updated: Jul 2, 2025

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改变COPD肺部和呼吸道上皮细胞中线粒体周转的分子控制

Christy B M Tulen1, Cheryl van de Wetering2, Caspar H J Schiffers2

  • 1School of Nutrition and Translational Research in Metabolism (NUTRIM), Department of Pharmacology and Toxicology, Maastricht University Medical Center+, Universiteitssingel 50, 6629 ER, Maastricht, The Netherlands.

Scientific reports
|February 27, 2024
PubMed
概括

在严重的COPD肺组织中,线粒体生物发生分子减少,而生物发生和线粒细胞发生因素增加. 这些变化在支气管上皮细胞中并不总是被观察到,这表明COPD在病变发生过程中具有复杂的作用.

关键词:
慢性阻塞性肺病是一种慢性阻塞性肺病.线粒体生物发生是线粒体生物发生.线粒细胞衰变 (mitophagy) 是一种细胞衰变的过程.周边肺组织的肺组织.主要的支气管上皮细胞

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