血液中挥发性有机芳香化合物度与美国成年人听力损失之间的关联
Senlin Wang1,2, Jing Luo1,3, Fang Zhang3
1College of Medicine, Southwest Jiaotong University, Chengdu, China.
BMC public health
|February 27, 2024
概括
对,乙和 (BEX) 的暴露与美国成年人听力损失的风险增加有关. 这项研究强调了这些挥发性有机化合物与低频和高频听力损伤之间的联系.
科学领域:
- 环境健康 环境健康
- 毒理学 毒理学 毒理学
- 听力学 听力学是指听力学.
背景情况:
- ,乙和 (BEX) 是关键的挥发性有机芳香化合物 (VOAC).
- 暴露于BEX可能会对人类健康产生负面影响.
- BEX暴露与听力损失 (HL) 之间的联系需要进行调查.
研究的目的:
- 评估美国成年人口中BEX暴露和听力损失之间的关系.
- 分析与整体听力损失的关联,特别是低频 (SFHL) 和高频听力损失 (HFHL).
主要方法:
- 使用来自国家健康和营养检查调查 (NHANES) (2003-2004,2011-2012,2015-2016) 的横截面数据.
- 包括人口统计,听力测量和血液BEX度数据.
- 使用加权多变量逻辑回归来检查BEX度和听力损失结果.
主要成果:
- 分析了2174名参与者的数据;HL,SFHL和HFHL的患病率分别为46.81%,25.23%和45.86%.
- 增加HL,SFHL和HFHL风险与暴露于单个BEX成分和累计BEX度 (所有P <0.05) 相关.
- 具体的几率比率 (ORs) 表明每个BEX组件和所有听力损失类型的整体BEX的风险增加.
结论:
- 在BEX暴露 (个人或累积) 与HL,SFHL和HFHL风险之间存在正相关性.
- 需要进一步的研究来了解BEX诱导的听力损失的机制.
- 建议进行纵向环境研究以验证这些发现.
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