维生素状态的评估;埃及新生儿的维生素A,E和D与IUGR:一个截面研究
Hanaa Reyad Abdallah1, Abderahman A Abdelrazek2, Eman Refaat Youness3
1Biological Anthropology Department, Medical Research and Clinical Studies Institute, National Research Centre, Cairo, Egypt. hanaareyad@yahoo.com.
BMC pediatrics
|February 27, 2024
概括
胎内生长迟缓 (IUGR) 的新生儿表现出较低的维生素A,E和D水平. 这些维生素缺乏与出生时体重,长度和头周的减少有关,这强调了对母亲的营养支持的需要.
科学领域:
- 新生儿医学 新生儿医学
- 营养科学 营养科学
- 生物化学 生物化学
背景情况:
- 子宫内生长迟缓 (IUGR) 对新生儿构成重大风险,包括潜在的致命并发症和长期发育问题.
- 母亲的维生素状况被认为是影响胎儿发育和新生儿结果的关键因素.
- 评估IUGR新生儿的维生素A,E和D水平对于了解他们的营养状况和潜在的健康影响至关重要.
研究的目的:
- 研究和比较被诊断患有IUGR的新生儿带血液中维生素A,E和D的度与适合妊娠年龄 (AGA) 的度.
- 探索带血维生素水平与新生儿人体测量 (体重,长度,头周长) 之间的相关性.
- 强调怀孕期间营养干预的重要性,以预防新生儿维生素缺乏.
主要方法:
- 收集了母亲数据和全面的新生儿评估,包括妊娠年龄,巴拉德得分,阿帕尔得分和人体测量测量 (头周长,长度,体重).
- 使用最后一次月经和超声波 (U/S) 来确定妊娠年龄.
- 在带血样本中的维生素A,E和D度使用高性能液态染色学 (HPLC) 和ELISA量化.
主要成果:
- 与AGA新生儿相比,IUGR新生儿的维生素A,E和D水平明显较低 (p <0.05).
- 在新生儿体重和带血中维生素A和E水平之间观察到显著的正相关性 (p <0.05).
- 新生儿长度仅与维生素A水平 (p < 0.05) 有显著的正相关性,而头周长与所有三种维生素都有正相关性 (p < 0.05).
结论:
- 患有IUGR的新生儿显示维生素A,E和D水平显著降低.
- 维生素A和E水平与出生体重,维生素A与新生儿长度正相关,而这三种维生素与IUGR婴儿的头周长相关.
- 这些发现强调了强有力的营养政策的必要性,以减轻怀孕期间和幼儿时期的维生素缺乏.
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