超声波可切换光温度计与双检测通道使用温度敏感脂质体
Tingfeng Yao1,2, Liqin Ren1,2, Baohong Yuan1,2
1Ultrasound and Optical Imaging Laboratory, Department of Bioengineering, The University of Texas at Arlington, Arlington, Texas, USA.
Journal of biophotonics
|February 28, 2024
概括
我们开发了一种新的非侵入性温度计技术,使用双色超声波可切换光 (USF) 进行精确的温度映射. 这种方法准确地测量生物组织中的局部温度,这对于理解代谢活动至关重要.
科学领域:
- 生物医学工程 生物医学工程
- 光学成像技术的成像
- 治疗监测 治疗监测
背景情况:
- 准确的温度测量对于研究生物过程和代谢活动至关重要.
- 现有的温度计方法在非侵入性,高分辨率的应用中可能存在局限性.
- 开发用于局部温度绘制的先进技术对于生物研究至关重要.
研究的目的:
- 引入和验证一种使用双色超声波切换光 (USF) 的新型非侵入性温度计技术.
- 为了使生物样本中的局部温度绘制能够使用温度敏感的脂质体.
- 评估USF温度计方法的准确性和可靠性,与既有技术相比.
主要方法:
- 使用双色超声波可切换光 (USF) 方法进行温度计.
- 采用温度敏感的脂质体作为局部温度传感的纳米成像剂.
- 分析了取决于温度的光发射和特征温度的出现时间.
- 采用基于摄像头的USF系统,具有两个检测通道和同时进行红外温度测试以验证.
主要成果:
- 根据脂质体光辐射,确定了四种特征温度.
- 通过分析动态USF信号,估计局部背景温度.
- 与红外热学相比,达到很高的准确度,与0.38°C ± 0.27°C的最小差异.
- 在36.48°C-40.14°C的生理温度范围内证明了可靠的性能.
结论:
- 双色USF温度计技术是一种可靠且非侵入性的温度测量方法.
- 这种技术为局部温度映射提供了出色的空间和热分辨率.
- USF温度计显示出在生物研究和代谢活动研究中应用的巨大潜力.
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Step 2: Turn on the thermometer and wait until the ready sign appears on the screen to ensure accurate measurement.
Step 3: Slide the probe cover in place to prevent cross-contamination.
Step 4: Instruct the patient to tilt their head to the side for comfort and check for cerumen...
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Step 1:
Start by practicing proper hand hygiene to prevent the spread of microorganisms.
Step 2:
Take the thermometer out of the charging unit, switch it on, and wait for the ready sign.
Step 3:
Gently slide the probe cover until a click is heard. This simple action prevents cross-contamination and ensures the correct placement of the probe cover.
Step 4:
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Step 1:
Start by practicing proper hand hygiene to prevent the spread of microorganisms.
Step 2:
Take the thermometer out of the charging unit, switch it on, and wait for the ready sign.
Step 3:
Gently slide the probe cover until a click is heard. This simple action prevents cross-contamination and ensures the correct placement of the probe cover.
Step 4:
Instruct the patient to open their mouth and place...
01:27Assessing Body Temperature - Rectal
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