基于天然产品的吸入配方用于治疗肺部疾病
Jiangyan Yong1, Hongli Shu1, Xiao Zhang2
1Department of Clinical Laboratory, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, 610072, People's Republic of China.
International journal of nanomedicine
|February 28, 2024
概括
吸入式纳米和微载体提供了一种有前途的方法,用于提供自然产品来治疗肺部疾病. 这一策略克服了传统疗法的局限性,改善了肺部药物输送和疾病管理.
科学领域:
- 肺部医学 肺部医学
- 纳米技术 纳米技术
- 药理学 药理学是指药理学的学科.
背景情况:
- 通过吸入直接的肺药物输送是肺部疾病的首选,避免全身毒性.
- 目前的吸入配方有限,传统设备难以到达特定的肺部区域.
- 癌症和纤维化等肺部疾病由于药物特性和输送挑战,缺乏有效的吸入治疗方法.
研究的目的:
- 审查基于纳米和微载体的天然产品可吸入配方的进展.
- 突出这些配方在治疗肺部疾病方面的潜力.
- 探索自然产品用于肺部疾病治疗的临床转化.
主要方法:
- 关于用于肺部药物输送的纳米和微载体系统的最新科学文献的审查.
- 分析自然产品在可吸入配方中的应用.
- 讨论针对深层肺组织的挑战和机会.
主要成果:
- 纳米和微粒子载体显示出有效将自然产品送到深层肺组织的潜力.
- 这些先进的配方可以克服传统吸入疗法的局限性.
- 向特定的肺部区域提供向的药物可以提高药物的疗效并减少副作用.
结论:
- 天然产品的可吸入纳米和微载体配方在治疗肺部疾病方面取得了重大进展.
- 这种方法提供了一种可行的策略,以解决目前肺部药物输送的局限性.
- 进一步的研究和开发有望为这些基于天然产品的疗法的实际临床转化提供希望.
相关概念视频
Inhaled Medications
258
Inhaled medications are crucial for managing chronic obstructive pulmonary disease (COPD) and asthma. They are essential for effective treatment and control, ensuring optimal respiratory health and well-being. Inhaled medication delivers drugs directly to the lungs, providing a rapid onset of action and reducing systemic side effects compared to oral or injectable medications. Three primary types of inhalation devices are used to administer these medications: nebulizers, metered-dose inhalers...
258
Drugs Used in Lower Respiratory Disorders: Overview
442
Lower respiratory tract disorders present challenges that often require skilled and nuanced approaches for effective management. Common ailments, such as asthma and chronic obstructive pulmonary disease (COPD), have prompted the development of intricate treatment strategies involving bronchodilators and anti-inflammatory drugs, each tailored to ease breathing and revitalize the lungs.
Bronchodilators, the first step of respiration enhancement, come in various forms, each with its own mechanism...
Bronchodilators, the first step of respiration enhancement, come in various forms, each with its own mechanism...
442
Asthma-IV: Diagnostic and Management
2.5K
The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
2.5K
Antiasthma Drugs: Inhaled Corticosteroids and Glucocorticoids
246
Inhaled corticosteroids (ICS) are anti-inflammatory drugs used primarily in treating persistent asthma and providing long-term maintenance. They target the bronchial mucosa, the lining of the airways, to control inflammation, a critical factor in asthma progression and exacerbation.
ICS work through a multifaceted mechanism of action. They suppress the inflammatory response caused by the proliferation of TH cells. They also reduce the transcription of the IL-2 gene, which is involved in the...
ICS work through a multifaceted mechanism of action. They suppress the inflammatory response caused by the proliferation of TH cells. They also reduce the transcription of the IL-2 gene, which is involved in the...
246
Drug Delivery: Miscellaneous Routes
338
Drug delivery methods like oral inhalation, nasal sprays, transdermal patches, eye drops, intravitreal injection, and rectal administration provide localized effects with reduced toxicity.
Oral inhalation and nasal sprays swiftly transfer drugs across the respiratory epithelium's mucosal layer. Inhaled glucocorticoids and bronchodilators directly target lung conditions such as asthma, while fluticasone nasal spray mitigates allergic rhinitis.
Transdermal patches transport drugs...
Oral inhalation and nasal sprays swiftly transfer drugs across the respiratory epithelium's mucosal layer. Inhaled glucocorticoids and bronchodilators directly target lung conditions such as asthma, while fluticasone nasal spray mitigates allergic rhinitis.
Transdermal patches transport drugs...
338
Drugs Used in Upper Respiratory Disorders: Overview
247
Upper respiratory tract disorders, including viral infections and allergic rhinitis, cause significant discomfort and disrupt daily life. Managing these conditions involves a variety of drugs, such as antihistamines, intranasal steroids, decongestants, antitussives, expectorants, and mucolytics. Specific examples of drugs in each category are provided.
Antihistamines (e.g., Benadryl) block histamines from binding. Histamines are chemicals released during an allergic reaction in the body. As a...
Antihistamines (e.g., Benadryl) block histamines from binding. Histamines are chemicals released during an allergic reaction in the body. As a...
247


