通过Saccharomyces cerevisiae的β-glucans强烈诱导受训免疫力

Patricia Vuscan1, Brenda Kischkel1, Aikaterini Hatzioannou2

  • 1Department of Internal Medicine and Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, Netherlands.

Frontiers in immunology
|February 28, 2024
PubMed
概括

一种Saccharomyces cerevisiaeβ-葡萄糖混合物通过激活关键受体和信号通路来增强人体单细胞中训练免疫力. 这种免疫训练减少了小鼠模型中的瘤生长,表明了治疗潜力.

相关概念视频

Vaccinations01:51

Vaccinations

Overview
44.5K
Immunological Memory01:23

Immunological Memory

Immunological memory, a pivotal pillar of the adaptive immune system, is responsible for the body's ability to remember and respond more swiftly and effectively to previously encountered pathogens. This remarkable feature is what makes vaccines so effective in preventing diseases.
What is Immunological Memory?
Immunological memory is an integral function of the immune system that allows it to recognize and react more rapidly and effectively to pathogens previously encountered. This feature...
611
Cells of the Adaptive Immune Response01:23

Cells of the Adaptive Immune Response

The T and B lymphocytes of the adaptive immune system develop from common lymphoid progenitor cells in the bone marrow. These progenitors give rise to precursors that eventually develop into both T and B lymphocytes. As these precursors mature, they gain the ability to detect and respond to foreign antigens in the body, a process known as immunocompetence. Additionally, these precursors acquire self-tolerance, a process that ensures they do not react to self-antigens. This intricate system...
986
B Cell Activation and Differentiation01:24

B Cell Activation and Differentiation

The adaptive immune response, a sophisticated defense mechanism, relies on the activation and differentiation of B lymphocytes, or B cells. These processes enable our bodies to mount a tailored response against specific pathogens such as bacteria, free virus particles, toxins, and parasites.
When naive B cells encounter a specific antigen that can bind to the B cell receptor (BCR) on their surface, they undergo sensitization to respond to the antigen's presence. Sensitization begins with...
1.7K
Cell-mediated Immune Responses01:40

Cell-mediated Immune Responses

Overview
68.3K