恶性贝塞斯达III结节的惰行为与贝塞斯达V/VI结节相比
Mayumi Endo1,2, Jing Peng3, Fadi A Nabhan1
1Division of Endocrinology, Diabetes, and Metabolism, The Ohio State University and Arthur G. James Cancer Center, Columbus, OH 43210, USA.
The Journal of clinical endocrinology and metabolism
|February 28, 2024
概括
通过贝塞斯达III细胞学诊断的甲状腺癌表现出不那么积极的临床过程和比贝塞斯达V/VI类别的更好的预后. 尽管诊断到手术的间隔较长,但贝塞斯达III型甲状腺癌的缓解速度更快,复发率更低.
科学领域:
- 内分泌学 在内分泌学.
- 在瘤学瘤学.
- 细胞病理学 细胞病理学
背景情况:
- 贝塞斯达系统报告甲状腺细胞病理学将精细针吸收标本分为六个诊断类别.
- 对于每个贝塞斯达类别内的甲状腺癌,人们假设了不同的临床行为.
研究的目的:
- 为了比较不同贝塞斯达类别 (III,IV,V和VI) 甲状腺癌的临床行为和预后.
主要方法:
- 556名患有甲状腺癌组织学诊断和初始贝塞斯达III,IV,V或VI细胞学的患者的回顾性分析.
- 临床结果的比较,包括手术的时间,缓解率,复发率和缓解的时间.
主要成果:
- 贝塞斯达III型甲状腺癌与V/VI型甲状腺癌具有组织学上的相似性,但与IV型甲状腺癌相比具有较少的侵袭性表型.
- 与贝塞斯达V/VI相比,贝塞斯达III患者从诊断到手术的间隔较长,但缓解速度更快,复发率更低.
- 复发的贝塞斯达III癌症通常是晚期 (T3/T4) 或转移性.
结论:
- 使用贝塞斯达III细胞学的甲状腺癌显示出较少的攻击性临床表型和更好的预后,而不是贝塞斯达V/VI细胞学.
- 贝塞斯达III的缓解时间较短,尽管诊断和手术之间的间隔较长.
- 使用贝塞斯达系统进行初始细胞学诊断可以为临床管理策略提供信息.
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