大麻使用与美国成年人心血管结果的关联
Abra M Jeffers1,2,3,4, Stanton Glantz5, Amy L Byers6,7,8
1Center for Tobacco Control Research & Education University of California San Francisco CA USA.
Journal of the American Heart Association
|February 28, 2024
概括
大麻使用与心脏病发作和中风等心血管事件的风险增加有关. 较重的使用,定义为每月更多的天数,与更高的心血管不良结果的几率相关.
科学领域:
- 心脏病学 心脏病学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 大麻使用很普遍,但其对心血管的影响需要进一步调查.
- 目前关于大麻和心血管健康的研究存在局限性.
- 了解这些风险对于公共卫生指导至关重要.
研究的目的:
- 调查大麻使用与心血管结果之间的关联.
- 在特定人群中分析这些关联:一般人群,从未吸烟的人,以及年轻人有早期心血管疾病风险.
主要方法:
- 这是一项基于人口的横截面研究,利用了2016-2020年行为风险因素监测调查的数据.
- 评估大麻使用频率 (过去30天中的几天) 和自我报告的心血管结果 (冠心病,心肌梗塞,中风).
- 采用多变量回归模型,对烟草使用和其他共变量进行调整.
主要成果:
- 在一般人群中,日常使用大麻与心肌梗塞 (aOR=1.25) 和中风 (aOR=1.42) 的几率增加有关.
- 在从未吸烟的吸烟者中,每日使用大麻与心肌梗塞 (aOR=1.49) 和中风 (aOR=2.16) 的相关性更强.
- 在早期心血管疾病风险较小的年龄组中,相关性一致.
结论:
- 大麻使用与不良的心血管结果有关.
- 增加大麻使用频率 (每月更多天) 与心血管事件的几率更高有关.
- 这些发现突出了与大麻消费相关的潜在心血管风险,特别是在特定的子组中.
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