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Updated: Jul 2, 2025

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对KRAS G12C抑制的计算洞察力:探索阿扎西提丁和利巴维林可能的重新用途

Vishakha Sharma1, Ankush Kumar1, Ravi Rawat2

  • 1Institute of Pharmaceutical Sciences, IET Bhaddal Technical Campus, Ropar, India.

Journal of biomolecular structure & dynamics
|February 28, 2024
PubMed
概括

这项研究研究了针对KRAS G12C癌症的核类药物. 阿扎西提丁和利巴维林显示出强大的结合潜力,这表明它们可以重新用于治疗依赖KRAS的癌症.

关键词:
在KRAS G12C中使用.这是一个RMSD.德西巴因 (decitabine) 是一种药物.药物重用是为了改变药物的用途.在体内进行的研究.分子对接的分子对接.

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