原发性甲状腺功能障碍症的副甲状腺切除术后PHQ-9和GAD-7评分响应:系统性审查和元分析
John Caraway1, Matthew Ryan2, Alex Yang2
1F. Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.
概括
副甲状腺切除术显著改善了原发性副甲状腺功能障碍症患者的抑郁和焦虑症状. 10或更高的PHQ-9分数可能表明需要手术.
科学领域:
- 内分泌学 在内分泌学.
- 神经外科 神经外科
- 精神病学是一个精神病学.
背景情况:
- 原发性偏甲状腺症 (PHPT) 与神经精神病症状有关.
- 副甲状腺切除术对这些症状的影响需要进一步定义.
研究的目的:
- 进行首次对手术前和手术后的PHQ-9和GAD-7得分进行元分析,这些得分在接受偏甲状腺切除术的PHPT患者中.
- 为了确定一个心理测量得分,可以指导手术干预决策.
主要方法:
- 在主要数据库 (PubMed,Embase,PsycINFO,Web of Science,Ovid) 中进行了全面的文献搜索.
- 包括的研究评估了PHQ-9和/或GAD-7在PHPT患者的副甲状腺切除术前和后的得分.
- 对汇编的数据进行了随机效应元分析.
主要成果:
- 六项研究 (1105名参与者) 符合纳入标准.
- 与对照组相比,PHPT患者的术前PHQ-9得分较高.
- 副甲状腺切除术导致PHQ-9得分显著且持续下降,临床显著抑郁症得分显著降低 (≥10).
结论:
- 副甲状腺切除术对PHPT患者的抑郁症得分 (PHQ-9) 有显著,持续的改善.
- 焦虑和自杀念头的症状似乎也会在手术后减少.
- PHQ-9分数≥10可能作为无症状PHPT的潜在手术指示.
关键词:
在GAD-7中,在 PHQ-9 时,我们会在 PHQ-9 时进行培训.焦虑是一种焦虑.抑郁 抑郁症 抑郁症 抑郁症 是一种神经精神病症状 神经精神病症状副甲状腺切除术 (parathyroidectomy) 是一种切除甲状腺的方法.原发性副甲状腺功能障碍症.心理测量查仪 心理测量查仪更多相关视频
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