多发性硬化症中的男性性和生殖健康:范围审查
Karlo Toljan1, Farren B S Briggs2
1Mellen Center for Multiple Sclerosis Treatment and Research, Neurological Institute, Cleveland Clinic, Cleveland, OH, 44195, USA. toljank@ccf.org.
Journal of neurology
|February 28, 2024
概括
性功能障碍在患有多发性硬化症 (MS) 的男性中很常见,影响生活质量. 患者和提供者之间关于MS的性和生殖健康的沟通缺口仍然存在.
科学领域:
- 神经学 神经学
- 生殖健康 生殖健康
- 公共卫生 公共卫生
背景情况:
- 多发性硬化症 (MS) 是一种慢性神经炎症性疾病,在生育年龄影响个体.
- 了解患有MS (MwMS) 的男性的性和生殖健康至关重要.
研究的目的:
- 确定和总结有关多发性硬化症男性性和生殖健康的现有数据.
- 突出MWMS中关于疾病修饰疗法和计划生育的知识差距.
主要方法:
- 根据PRISMA扩展指南进行范围审查.
- 使用关键词搜索PubMed与多发性硬化症,性健康,生殖健康,生育能力和功能障碍相关.
- 描述性分析包括34项研究.
主要成果:
- 性功能障碍影响MWMS的35-72%,勃起功能障碍和性欲下降是最常见的.
- 多发性硬化障碍和抑郁症与性功能障碍相关;固酶-5抑制剂对勃起功能障碍显示出有效性.
- 关于在MWMS中使用疾病修饰疗法和计划生育的重大知识差距存在.
结论:
- 性功能障碍在MWMS中普遍存在,对生活质量产生负面影响,并受MS严重程度的影响.
- 沟通障碍阻碍了MWMS和医疗保健提供者之间关于性/生殖健康的讨论.
- 需要进一步研究多发性硬化疗法对性和生殖健康的影响.
相关概念视频
Disorders of the Male Reproductive System
414
Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
414
Male Sexual Response: Erection & Ejaculation
2.3K
Sexual stimulation can take various forms, such as physical touch and visual or auditory cues. When this happens, the parasympathetic reflex in the sacral portion of the spinal cord is activated. This reflex stimulates the release of nitric oxide (NO), which then dilates the arterioles in the penis, increasing blood flow to the erectile tissues - the corpora cavernosa and corpus spongiosum.
The blood filling the erectile tissues compresses the veins, which helps to prevent blood from leaving...
The blood filling the erectile tissues compresses the veins, which helps to prevent blood from leaving...
2.3K
Infertility in Males
262
Male infertility affects millions of couples worldwide, arising from various factors that impact different stages of the reproductive process. An endocrine imbalance resulting from conditions like hypogonadism, Klinefelter syndrome, or pituitary disorders can disrupt hormone levels and reduce sperm production. Testicular defects, such as tumors, cryptorchidism, atrophic testes, abnormal sperm morphology, and low sperm count or motility, may arise due to genetic factors, structural...
262


