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Updated: Jul 2, 2025

Activation and Measurement of NLRP3 Inflammasome Activity Using IL-1β in Human Monocyte-derived Dendritic Cells
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Published on: May 22, 2014

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在HSP90β控制NLRP3自动激活.

Lotte Spel1, Cyrielle Hou1, Katerina Theodoropoulou1,2

  • 1Department of Immunobiology, University of Lausanne, 155 Ch. des Boveresses, Epalinges 1066, Switzerland.

Science advances
|February 28, 2024
PubMed
概括

HSP90β-SGT1复合体对于冷皮林相关周期性综合征 (CAPS) 中的NLRP3炎症酶激活至关重要. 抑制HSP90β可以通过减少IL-1β分泌来治疗CAPS.

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