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Updated: Jul 2, 2025

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使用宏观循环选择性修改和蛋白质的近期进展

Ye-Cheng Wang1,2, Si-Cong Bai3, Wei-Lin Ye1,2

  • 1Fuzhou Institute of Oceanography, College of Materials and Chemical Engineering, Minjiang University, Fuzhou, Fujian 350108, China.

Bioconjugate chemistry
|February 28, 2024
PubMed
概括

宏循环为选择性和蛋白质修饰提供了一种新的方法,增强了药物开发和稳定中的应用. 这种宿主-客人化学方法对先进的生物结合策略有前途.

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Because the DNA segments are cut and reorganized in a direction-specific manner, site-specific recombination has emerged as an efficient genetic engineering technique. Flippase and Cyclization recombinases or Flp and Cre, respectively, are two members of the tyrosine recombinase family derived from bacteriophages, that are used to mediate site-specific DNA insertions, deletions, and targeted expression of proteins in mammalian cell lines.
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