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Updated: Jul 2, 2025

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综合的多omics分析揭示了肠道微生物群失调和系统性干扰在严重抑郁症中

Zuoquan Xie1, Jingjing Huang2, Guangqiang Sun3

  • 1State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.

Psychiatry research
|February 28, 2024
PubMed
概括

大型抑郁症 (MDD) 改变肠道细菌和血液代谢物,影响免疫细胞. 本研究确定了MDD的关键差异和潜在生物标志物.

关键词:
生物标志物 生物标志物我们的肠道微生物群.免疫表型的形成大型抑郁症主要是抑郁症.多种组合的多种组合.周边的变化 周边的变化

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Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...
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